As things stand, Al Hilal hold a three-goal lead over Al Sadd ahead of their clash in Riyadh on Tuesday and Urawa take a two-goal advantage to southern China a day later. With the final line-up to be confirmed this week, here’s the-AFC.com’s five things to look out for.

Seven times Guangzhou have faced J.League opponents in the AFC Champions League knockout stage, and seven times it has been the southern Chinese side that has emerged victorious.

But at Tianhe Stadium on Wednesday, they face arguably their biggest test yet as they are up against an Urawa side that bring with them a 2-0 lead from the first leg.

A veteran of 12 AFC Champions League tournaments so far, and a winner in 2013 and 2015, Huang Bowen knows full well the challenge his side face.

In 2007, Urawa made history as the first J.League club to be crowned Continental kings since Asia's premier club tournament underwent a revamp in 2002-03 to become the AFC Champions League.

A decade later, Urawa repeated their efforts to join Wednesday's opponents Guangzhou, Korea Republic's Jeonbuk Hyundai Motors and Al Ittihad of Saudi Arabia as the only two-time winners of the AFC Champions League.

Gomis and Leonardo – who has left Al Wahda to join Shabab Al Ahli since the Emirati side were eliminated – are tied with nine goals apiece, but with the Saudi team potentially having three more games to play, the Frenchman is the favourite to win the top scorer award come November 24.

But, while one more goal would see the Al Hilal target man take pole position, there remains a chasing pack who will have one eye on the accolade. Ahead of the semi-final second legs next week, the-AFC.com takes a closer look at the contenders.

Following the international break, the domestic action in East Asia returned with a bang as the leagues in Japan, Korea Republic and China PR enter the business end of season, while the Hong Kong and Mongolia Premier Leagues also saw some intriguing ties.

Al Sadd, who face Al Hilal in Tuesday's Continental semi-final, were not in action as their Qatar Stars League tie was postponed, UAE Pro League defending champions Sharjah continued their perfect record and Kuwait SC maintained their unbeaten run in Kuwait.

Join the-AFC.com reviews the domestic action in West Asia.

Trailing 2-0 from the first leg in Japan after goals from Fabricio and Takahiro Sekine, two-time Continental champions Guangzhou are up against it when they host Urawa at Tianhe Stadium in the return meeting of their final four tie.

However, the southern Chinese heavyweights have not yet lost hope. A 21-match unbeaten record in the AFC Champions League on home soil is an excellent foundation for faith and a stacked attacking line-up including some of China and Brazil's top talent is capable of finding the goals needed.