Group A: Esteghlal FC (IRN) 2-0 Al Wehdat (JOR)

Shahr-E Qods: Esteghlal FC secured their first win in the AFC Champions League Two™ 2025/26 after defeating Al Wehdat 2-0 in their Group A tie on Wednesday.

Group B: PFC Andijon (UZB) 0-0 Al Khaldiya SC (BHR)

Andijan: Al Khaldiya SC’s perfect start in the AFC Champions League Two™ 2025/26 came to an end after they were held to a goalless draw by PFC Andijon on Wednesday.

Group D: FC Goa (IND) 1-2 Al Nassr Club (KSA)

Goa: Al Nassr Club staved off a fightback from FC Goa to walk away with a 2-1 win from their AFC Champions League Two™ 2025/26 Group D tie at the Pandit Jawaharlal Nehru Stadium on Wednesday.

Group D: FC Istiklol (TJK) 2-1 Al Zawraa SC (IRQ)

Hisor: Paul Komolafe came off the bench to snatch a late winner as FC Istiklol reversed a deficit to edge Al Zawraa 2-1 in their AFC Champions League Two™ 2025/26 Group D tie at the Hisor Central Stadium on Wednesday.

Group F: Ratchaburi FC (THA) 5-1 Eastern FC (HKG)

Ratchaburi: A hat-trick by Denilson Junior helped Ratchaburi FC defeat Eastern FC 5-1 and claim their first AFC Champions League Two™ 2025/26 Group F win at the Ratchaburi Stadium on Wednesday.

Group F: Gamba Osaka (JPN) 3-1 Nam Dinh FC (VIE)

Suita: Gamba Osaka surged to their third consecutive AFC Champions League Two™ 2025/26 Group F win with a comfortable 3-1 defeat of Nam Dinh FC at the Suita City Football Stadium on Wednesday.